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Abdomen or duodenal ulcer. For those who have a abdomen ulcer or duodenal ulcer, prednisone could allow it to be even worse. Using prednisone by having an NSAID (soreness reliever) for example ibuprofen also can improve your risk of building or worsening an ulcer. In case you have 1 of those ulcers, talk with your physician about regardless of whet